@jarat @jcaron So i tried your second option, and i saw a drop in current consumption to about 70 mA from 77mA. And this option did NOT turn of the LoPy. And i further tried to read from the I2C to get the GPS coordinates while it was off and i got an error. So i might think that the second option worked, but a drop of 7 mA is maybe a bit too little to come from the GPS? The datasheet of the GPS says that the gps should use around 29 ma. So i should have measured a current consumption around 50 mA?