@ahmadelmasri I solved this with a tip from the README. Python version was incompatible.

Woo Hoo!! 🙏🏼💃🏽💥🎉🎉 Thanks, I guess I assumed that the expansion board was just the drivers for an onboard serial port. Next time, I'll look at the schematics as well, since the WiPy docs said that there wasn't any driver needed for use. It's all working, now I can geek out having combined my two favorite worlds... embedded systems and Python!