You'll might have issue attaching to the network again, in which case you'll have to deinit and try re-attaching. Probably won't be an issue unless you save some state to nvram. I don't understand the other part fully: Are you using all three commands to deinit the LTE modem? I think you only need lte.deinit() or the other two (although I'm looking for a definite answer to this as we speak). What do you estimate to power consumption difference to be? What power consumption/battery life do you need to achieve?

@jmarcelino With pycom.wifi_on_boot(False), I started using rshell, which I truly enjoy. It allows me to keep on writing code with vim (instead of atom) whilst rendering the upload and running of scripts really easy. The rshell command line tool definitely also merits mentioning in the documentation.