@Dezert754 You have to connect the GND of both devices and a Pin of the Wipy set as Output to a Pin of the Arduino set as Input. The cables should not be long, and adding a resistor of 4.7kOhm into the wire does not hurt. Since the WiPy runs at 3.3 V and the Arduino at 5V, the level at the Arduino for a high is specified as 3.5V, so it's not sure if it works. Better use a level converter.

@hansjorg2 Ampy is a a python program. You'll find it here: https://learn.adafruit.com/micropython-basics-load-files-and-run-code/install-ampy

To upload a whole project to the pycom board with Visual Studio Code, one has to the File > Open Folder command. Choose the folder where all your .py files are in, e.g., main.py, boot.py and so on. By opening the folder instead of a single file, the IDE and pymakr recognizes all files and interprets them as project. It took me ages to understand how this works... There are so many tutorials and guides around pycom, but there is not guide going through really ALL steps.