R
Ok by following this guide and using the config below I have my LoPy running through a Jupyter notebook.
In kernel.json:
{
"argv": ["python3",
"-m", "jupyter_micropython_kernel",
"/dev/cu.usbmodemPy343431", "115200",
"-f", "{connection_file}"],
"display_name": "MicroPython",
"language": "micropython"
}